Clinical evidence Metabolic

Semaglutida

GLP-1 receptor agonist

Long-acting GLP-1 agonist for glycemic and weight control.

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Class
GLP-1 receptor agonist
Also known as
Marketed under various brands (e.g. Ozempic®, Wegovy®, Rybelsus®)

Mechanism of action

Selective GLP-1 receptor agonist. It enhances glucose-dependent insulin secretion, suppresses glucagon, slows gastric emptying and increases central satiety. Its modification (an amino-acid substitution plus a fatty-acid chain that binds albumin) gives it a ~1-week half-life.

Evidence

Clinical evidence

Solid clinical evidence: regulatory approval and large trial programs (SUSTAIN, STEP, SELECT), including cardiovascular outcomes.

Studied uses

  • Type 2 diabetes mellitus (glycemic control)
  • Obesity and overweight with comorbidity
  • Cardiovascular risk reduction in specific populations

Safety considerations

  • Frequent gastrointestinal effects (nausea, vomiting, diarrhea)
  • Medullary thyroid carcinoma / MEN2 warning (contraindicated with personal or family history)
  • Caution with pancreatitis; do not use in pregnancy

Batch quality data

We publish these figures because they are the ones the program itself teaches you to ask for.

Purity
≥ 99 % (HPLC)
Net content
82 %
Batch
SEM-2601
Presentation
Polvo liofilizado en vial sellado

Net content is the fraction of the vial’s weight that is actually peptide, after discounting water, salts and excipients. It is the figure to calculate with, not the label weight.

5 mg MX$1,650 per vial
10 mg MX$2,890 per vial

Sample prices and batch data while the real ones are loaded.

Educational reference sheet. It is not a recommendation to use, a clinical indication or a protocol. Many of these compounds are marketed for research use only and are not approved for human use. Always cross-check with the primary literature and the regulation in your country.