Technical sheets

Technical reference sheets

Fifteen of the most studied peptides, with mechanism of action, evidence and considerations — each labeled by its real level of evidence.

Clinical evidence

Semaglutida

GLP-1 receptor agonist

Long-acting GLP-1 agonist for glycemic and weight control.

Clinical evidence

Tirzepatida

GIP/GLP-1 co-agonist (dual incretin)

Dual incretin agonist with marked metabolic and weight effect.

Investigational

Retatrutida

GIP/GLP-1/glucagon triple agonist

Triple agonist in clinical development for obesity and metabolism.

Investigational

Cagrilintida

Long-acting amylin analogue

Amylin analogue that reinforces satiety; studied alone and combined.

BPC-157

Pentadecapeptide (sequence derived from a gastric protein)

Repair peptide with mostly preclinical evidence.

TB-500

Synthetic fragment related to thymosin β4

Fragment associated with cell migration and angiogenesis (proposed).

Investigational

Ipamorelina

Selective GH secretagogue (ghrelin receptor / GHS-R agonist)

Selective secretagogue that stimulates pulsatile GH release.

Investigational

CJC-1295

Long-acting GHRH analogue

GHRH analogue that prolongs GH/IGF-1 stimulation.

Clinical evidence

Tesamorelina

Stabilized GHRH analogue

GHRH analogue approved to reduce visceral fat in HIV lipodystrophy.

Clinical evidence

Sermorelina

GHRH analogue (fragment 1-29)

GHRH fragment historically used in GH diagnosis.

GHK-Cu

Copper tripeptide (glycyl-histidyl-lysine copper complex)

Copper peptide studied in dermal remodeling and cosmetics.

Clinical evidence

PT-141 (Bremelanotida)

Melanocortin receptor agonist (MC4R)

Melanocortin agonist approved for hypoactive sexual desire.

Melanotan-2

Synthetic α-MSH analogue (non-selective melanocortin agonist)

Melanocortin analogue linked to melanogenesis; not approved.

Semax

Heptapeptide derived from ACTH (4-10)

Neuromodulator with mostly preclinical evidence outside Russia.

Epitalón

Tetrapeptide (Ala-Glu-Asp-Gly)

Tetrapeptide with longevity hypotheses and very limited evidence.

Educational reference sheet. It is not a recommendation to use, a clinical indication or a protocol. Many of these compounds are marketed for research use only and are not approved for human use. Always cross-check with the primary literature and the regulation in your country.